NON-CANONICAL HEDGEHOG SIGNALING IS A POSITIVE REGULATOR OF THE WNT PATHWAY AND IS REQUIRED FOR THE SURVIVAL OF COLON CANCER STEM CELLS

Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells

Summary: Colon cancer is a heterogeneous tumor driven by a subpopulation of Moss Wall Art cancer stem cells (CSCs).To study CSCs in colon cancer, we used limiting dilution spheroid and serial xenotransplantation assays to functionally define the frequency of CSCs in a panel of patient-derived cancer organoids.These studies demonstrated cancer organ

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Stenting of Variant Left Carotid Artery Using Brachial Artery Approach in a Patient with Unusual Type of Bovine Aortic Arch

Bovine aortic arch is the most frequently encountered variation in human aortic arch branching.A 63-year-old Asian male presented with symptomatic severe stenosis of left carotid artery originating from the brachiocephalic trunk.Selective engagement to the left carotid artery LIGHT YELLOW MISO was unsuccessful using transfemoral BOSCH Serie 4 KGN39

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A Recombinant Snake Cathelicidin Derivative Peptide: Antibiofilm Properties and Expression in Escherichia coli

The emergence of antimicrobial resistance among pathogenic microorganisms has been led to an urgent need for antibiotic alternatives.Antimicrobial Eyelashes peptides (AMPs) have been introduced as promising therapeutic agents because of their remarkable potentials.A new modified cathelicidin-BF peptide (Cath-A) with 34 amino acid sequences, represe

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